Together We Will Advance Research

8th Annual DTRF Int’l Desmoid Tumor Research Workshop (Virtual via Zoom)

Friday, September 24th
11am EDT | 5pm CEST | 10am CDT | 9am MDT | 8am PDT 

The DTRF International Research Workshop features:
  • A forum to share research findings, develop new collaborations, bring new scientists into the research field, and work together on new innovations that will lead to new treatments
  • Pre-recorded scientific talks on current research that attendees are encouraged to watch in advance of the meeting
  • Live questions and discussions relating to the scientific talks
  • Group discussions focusing on gaps in desmoid tumor science and how best to address them through high impact collaborative research

Why should you join us?
    • You’ll play a key role in helping prioritize areas where DTRF should be directing resources and activities in the future
    • You’ll be a part of the momentum that propels the field forward
    • You’ll develop collaborations with a diverse group of scientists and the brightest minds in desmoid tumor research and treatment
Our distinguished presenters

Associate Professor of Pediatrics, Maine Medical Center (Chair, DTRF Medical Advisory Board)

PhD candidate, Surgical Oncology, Erasmus Medical Center Cancer Institute

Professor & Chair, Orthopaedic Surgery, Duke University

Associate Professor, University of Colorado Anschutz Medical Campus

Associate Professor at the Keck School of Medicine and Medical Director of Clinical Research Support Office for the Cancer and Blood Disease Institute at Children’s Hospital Los Angeles

Assistant Professor, Department of Pathology, Stanford University School of Medicine

Executive Medical Director, Ayala Pharmaceuticals

The Desmoid Tumor Research Foundation

Scientific Director, Cancer Dependency Map, The Broad Institute of MIT and Harvard

Instructor, Department of Pathology, Stanford University

Adjunct Associate, Duke University and Medical Science Liaison, Jazz Pharmaceuticals, Inc.

Professor of Developmental Biology, Ghent University

Head, Molecular and Systems Oncology Laboratory, Division of Molecular Pathology, The Institute of Cancer Research

Medical Oncologist, All India Institute of Medical Sciences

Patient and DTRF Advocate

Medical Oncologist, University Hospital Virgen del Rocio

Int’l Desmoid Tumor Research Workshop (Virtual via Zoom)
Friday, September 25th 
11am EDT | 5pm CEST | 10am CDT | 9am MDT | 8am PDT 

Workshop Agenda 

11:00- 11:05 AM
Welcome: Jeanne Whiting, President and Co-Founder, DTRF.

11:05- 11:15 AM
Benjamin Alman, MD, Professor & Chair, Orthopaedic Surgery, Duke University, “Mouse models in desmoid tumors.”

11:15- 11:25 AM
Jesse Boehm, PhD, Scientific Director of the Cancer Dependency Map, Associate Director of the Cancer Program, Director of the Broad Cancer Model Development Center, The Broad Institute of MIT and Harvard, “The Desmoid Tumor Dependency Map.” ABSTRACT

11:25- 11:35 AM 
Kris Vleminckx, PhD, Professor of Developmental Biology, Ghent University, “Identifying and characterizing dependency factors in a genetic Xenopus tropicalis desmoid tumor model.”  ABSTRACT

11:35- 11:45 AM
Paul Huang, PhD, Head, Molecular and Systems Oncology Laboratory, Division of Molecular Pathology, The Institute of Cancer Research, “Deconstructing the desmoid tumour matrisome.”  ABSTRACT

11:45- 11:55 AM
Kelly Mercier, PhD, Adjunct Associate, Duke University; Medical Science Liaison, Jazz Pharmaceuticals, Inc., “Stable isotope resolved metabolomics to interrogate the interactions between stroma and desmoid tumors.” ABSTRACT

11:55 AM- 12:05 PM
Joanna Przybyl, PhD, Instructor, Department of Pathology, Stanford University, “Genome-wide DNA methylation profiling of desmoid tumors.”  ABSTRACT

12:05- 12:15 PM
Gerlinde Wernig, MD, Assistant Professor, Department of Pathology, and Tristan Lerbs, PhD, Post doctoral Researcher, Stanford University School of Medicine, “Jun and its Connections with Wnt and Notch.”  ABSTRACT

12:15- 12:45 PM
GROUP PHOTO & GROUP DISCUSSION

12:45- 12:55 PM
Anne-Rose W Schut, MD, PhD candidate, Surgical Oncology, Erasmus Medical Center Cancer Institute, “The mechanism of Sorafenib in desmoid-type fibromatosis.”  ABSTRACT

12:55- 1:05 PM
Javier Martin Broto, MD, PhD, Instituto de Biomedicina de Sevilla (IBIS), “Activity of taxanes in progressive or symptomatic desmoid tumors.ABSTRACT

1:05- 1:15 PM
Breelyn A. Wilky, MD, Associate Professor, University of Colorado Anschutz Medical Campus, “Association of CTNNB1 mutation subtypes with responses to systemic therapy in patients with desmoid tumors.”  ABSTRACT

1:15- 1:30 PM
15 MINUTE DISCUSSION

1:30- 1:35 PM
Christina Kosyla, Desmoid tumor patient and advocate.

1:35- 1:45 PM
Sameer Rastogi, MD, Medical Oncologist, All India Institute of Medical Sciences, “Desmoid fibromatosis management in tertiary care center in India- Lessons learned.”  ABSTRACT

1:45- 1:55 PM
Aaron Weiss, DO, Associate Professor of Pediatrics, Maine Medical Center (Chair, DTRF Medical Advisory Board), “The DTRF Virtual Tumor Board.” ABSTRACT

1:55- 2:05 PM
Kelly Mercier, PhD, Adjunct Associate, Duke University; Medical Science Liaison, Jazz Pharmaceuticals, Inc., “The DTRF Natural History Study.” ABSTRACT

2:05- 2:15 PM
Chen Duksin, MD, MBA, Executive Medical Director, Ayala Pharmaceuticals, AL102, Oral Gamma-Secretase Inhibitor for the Treatment of Patients Living with Desmoid Tumors.” ABSTRACT

2:15- 2:25 PM
Fariba Navid, MD, Associate Professor at the Keck School of Medicine and Medical Director of Clinical Research Support Office for the Cancer and Blood Disease Institute at Children’s Hospital Los Angeles, “ARST1921: A Safety Pharmacokinetic and Efficacy Study of a y-Secretase Inhibitor, Nirogacestat (PF-03084014), in Children with Adolescents with Progressive, Unresectable Desmoid Tumors.” ABSTRACT

2:25- 2:50 PM
SUMMARY DISCUSSION & SETTING OF PRIORITIES