Together We Will Advance Research

8th Annual DTRF Int’l Desmoid Tumor Research Workshop
For Medical Professionals Only
(Virtual via Zoom)

Friday, September 24th, 10:30am- 3:30pm EDT
4:30pm CEST | 9:30am CDT | 8:30am MDT | 7:30am PDT | Time zone converter

REGISTER

The DTRF International Research Workshop will be held in conjunction with our Patient Meeting webinars which take place the following day, Saturday, September 25th. Medical professionals are encouraged to attend both the workshop and the webinars if possible.

Last year, our Virtual International Research Workshop grew exponentially from its prior year. Over 190 physicians and researchers registered, expanding our worldwide participation to 72 institutions from 31 countries.

The DTRF International Research Workshop features:
  • A forum to share research findings, develop new collaborations, bring new scientists into the research field, and discuss new innovations that will lead to new treatments

  • Pre-recorded scientific talks on current research that attendees are encouraged to watch in advance of the meeting
  • Live questions and discussions relating to the scientific talks
  • Group discussions focusing on gaps in desmoid tumor science and how best to address them through high impact collaborative research

Why should you join us?
    • You’ll develop collaborations with a diverse group of scientists and the brightest minds in desmoid tumor research and treatment
    • You’ll play a key role in helping prioritize areas where DTRF should be directing resources and activities in the future
    • You’ll be a part of the momentum that propels the field forward
Our distinguished presenters (as of 6/15/21)

Professor & Chair, Orthopaedic Surgery, Duke University

Senior Researcher, Laboratory of Tumor Biology and Biomarkers, A.C. Camargo Cancer Center

Sarcoma Department, IEO Istituto Europeo di Oncologia

Strasbourg’s University Hospitals

Associate Professor, Department of General Surgery, Faculty of Medicine, University of Toronto

Chief Medical Officer, Ayala Pharmaceuticals

Medical Director, Ayala Pharmaceuticals

Department of Internal Medicine, Yonsei University

Research Director, DTRF Coordinating Center

Rehabilitation & Orthopedic Oncology, Nagoya University Graduate School of Medicine

Kelly Mercier, PhD

Principal Investigator, DTRF Patient Registry & Chair, DTRF Coordinating Center

Director of Clinical Research & Innovation Dept/ Head of General Oncology in Medical Oncology, Oscar Lambret Cancer Center

Associate Professor, Dept. of Medical Oncology, All India Institute of Medical Sciences (AIIMS), New Delhi

PhD candidate, Surgical Oncology and Medical Oncology, Erasmus Medical Center Cancer Institute

Researcher, “Mauro Baschirotto” Institute for Rare Diseases – BIRD Foundation

Transplant Gastroenterologist, Medstar Georgetown University Hospital

Professor of Developmental Biology, Ghent University

Assistant Professor, Department of Pathology, Stanford University School of Medicine

SpringWorks Therapeutics, Inc.

The Desmoid Tumor Research Foundation

Int’l Desmoid Tumor Research Workshop (Virtual via Zoom)
Friday, September 24th 
10:30am EDT | 4:30pm CEST | 9:30am CDT | 8:30am MDT | 7:30am PDT | Time zone converter

DRAFT Workshop Agenda 

10:30- 10:35 am
Welcome: Jeanne Whiting, President and Co-Founder, DTRF.

10:35- 10:45 am
Benjamin Alman, MD, Professor & Chair, Orthopaedic Surgery, Duke University, and Maneesh Kumar, MD, PhD, Research Director, DTRF Coordinating Center, Welcome/DTRF Updates.

10:45- 10:55 am
Yoshihiro Nishida, MD, Rehabilitation & Orthopedic Oncology, Nagoya University Graduate School of Medicine, “Diagnostic and therapeutic strategies for extra-abdominal desmoid-type fibromatosis: a longitudinal questionnaire survey to specialized centers in Japan.” ABSTRACT

10:55- 11:05 am
Hyo Song Kim, MD, Department of Internal Medicine, Yonsei University, “Genomic and transcriptomic analysis of desmoid tumor reveals enrichment of transforming growth factor beta responsive signature.”

11:05- 11:15 am
Afshin Gangi, MD, PhD, Strasbourg’s University Hospitals, “Evaluation of the Cryodestruction of Non- Abdominopelvic Desmoid Tumors in Patients Progressing despite Medical Treatment (CRYODESMO01).”

11:15- 11:25 am
Nicholas Penel, MD, PhD, Director of Clinical Research & Innovation Dept/ Head of General Oncology in Medical Oncology, Oscar Lambret Cancer Centre. “Prognosis value of S45F mutation of CTNNB1 in desmoid-type fibromatosis (DF). Prospective analysis of 500 consecutive patients (pts) from ALTITUDES Trial.” ABSTRACT

11:25- 11:35 am
Sara Coppola, MD, Sarcoma Department, IEO Istituto Europeo di Oncologia, “Abdominal Desmoid Tumors: A series from a single institution.” ABSTRACT

11:35- 11:45 am
NORD/C-PATH, RDCP- DAP/Data-sharing

11:45 am- 12:15 pm
Group Photo/ Summary Discussion/ Priorities

12:15- 12:35 pm
KEYNOTE: 
Stefani Spranger, PhD, Assistant Professor of Biology, Massachusetts Institute of Technology, IO/Beta-catenin/Melanoma

12:35- 12:45 pm
Kris Vleminckx, PhD, Professor of Developmental Biology, Ghent University, “Investigating the mechanisms and tumor-host interactions mediating desmoid tumor regression by EZH2 inhibition in CRISPR-based Xenopus tropicalis models.”

12:45- 12:55 pm
Gerlinde Wernig, MD, Assistant Professor, Department of Pathology, Stanford University, New Research – CD47 blockade.

12:55- 1:05 pm
Mushriq Al-Jazrawe, PhD, Post-doctoral Associate, The Broad Institute of MIT and Harvard, “Developing a physiologically relevant target validation platform for desmoid tumors.”

1:05- 1:15 pm
Daniela Segat, PhD, Researcher, “Mauro Baschirotto” Institute for Rare Diseases – BIRD Foundation, “CRISPR/Cas9 approach for creating a simplified cellular model to study the Desmoid cells in response to external stimuli and in cellular communication.” ABSTRACT

1:15- 1:25 pm
Ludmilla Thome Domingos Chinen, PhD, Senior researcher, Pesquisadora Hospital ACCamargo- Fundação Antônio Prudente, “Circulating tumor cells in desmoid tumors.”

1:25- 1:35 pm
Sameer Rastogi, MD, Associate Professor, Dept. of Medical Oncology, All India Institute of Medical Sciences (AIIMS), New Delhi, “Patient reported outcomes in patients with desmoid type fibromatosis.” ABSTRACT

1:35- 1:45 pm
Sukanya Subramanian, MD, Transplant Gastroenterologist, Medstar Georgetown University Hospital, “Intestinal transplant as rescue therapy.” ABSTRACT

1:45- 2:05 pm
Break + Summary Discussion

2:05- 2:10 pm
Desmoid Patient Advocate

2:10- 2:20 pm
Gary Gordon, MD, PhD,
Chief Medical Officer, and Jason Kaplan, MD, Medical Director, Ayala Pharmaceuticals, “AL102, Investigational Oral Gamma-Secretase Inhibitor for the Potential Treatment of Desmoid Tumors.” ABSTRACT

2:20- 2:30 pm
Jessica White, PhD student, SpringWorks Therapeutics, Inc., “The Epidemiology of Desmoid Tumors in Denmark.” ABSTRACT

2:30- 2:40 pm
Anne-Rose Schut, MD, PhD candidate, Surgical Oncology and Medical Oncology, Erasmus Medical Center Cancer Institute, “The evaluation of health-related quality of life issues experienced by patients with desmoid-type fibromatosis (The QUALIFIED STUDY).” ABSTRACT

2:40- 2:50 pm
Kelly Mercier, PhD, Principal Investigator, DTRF Patient Registry & Chair, DTRF Coordinating Center, “DTRF’s Natural History Study.”

2:50- 3:00 pm
Rebecca Gladdy, MD, PhD, Associate Professor, General surgery, University of Toronto, “FAP Desmoid or pregnancy associated disease and considerations.”

3:00- 3:10 pm
Chandrajit Raut, MD, MSc, Professor of Surgery,  Harvard Medical School Chief, Division of Surgical Oncology, Department of Surgery, Brigham and Women’s Hospital Surgery Director, Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Pregnancy Study.

3:10- 3:30 pm
Summary Discussion + Wrap Up